Technical Comments

Response to Comment on “The hologenomic basis of speciation: Gut bacteria cause hybrid lethality in the genus Nasonia

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Science  29 Aug 2014:
Vol. 345, Issue 6200, pp. 1011
DOI: 10.1126/science.1256708


Chandler and Turelli postulate that intrinsic hybrid dysfunction underscores hybrid lethality in Nasonia. Although it is a suitable conception for examining hybrid incompatibilities, their account of the evidence is factually inaccurate and leaves out the evolutionary process for why lethality became conditional on nuclear-microbe interactions. Hybrid incompatibilities in the context of phylosymbiosis are resolved by hologenomic principles and exemplify this emerging postmodern synthesis.

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