Research Article

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

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Science  26 Sep 2014:
Vol. 345, Issue 6204, 1251086
DOI: 10.1126/science.1251086

Article Information

vol. 345 no. 6204

PubMed: 
Print ISSN: 
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History: 
  • Received for publication January 20, 2014
  • Accepted for publication August 28, 2014
  • .

Author Information

  1. Sadia Saeed1,*,
  2. Jessica Quintin2,*,
  3. Hindrik H. D. Kerstens1,*,
  4. Nagesha A. Rao1,*,
  5. Ali Aghajanirefah1,*,
  6. Filomena Matarese1,
  7. Shih-Chin Cheng2,
  8. Jacqueline Ratter2,
  9. Kim Berentsen1,
  10. Martijn A. van der Ent1,
  11. Nilofar Sharifi1,
  12. Eva M. Janssen-Megens1,
  13. Menno Ter Huurne1,
  14. Amit Mandoli1,
  15. Tom van Schaik1,
  16. Aylwin Ng3,4,
  17. Frances Burden5,6,
  18. Kate Downes5,6,
  19. Mattia Frontini5,6,
  20. Vinod Kumar7,
  21. Evangelos J. Giamarellos-Bourboulis8,
  22. Willem H. Ouwehand5,6,
  23. Jos W. M. van der Meer2,
  24. Leo A. B. Joosten2,
  25. Cisca Wijmenga7,
  26. Joost H. A. Martens1,
  27. Ramnik J. Xavier3,4,
  28. Colin Logie1,,
  29. Mihai G. Netea2,,
  30. Hendrik G. Stunnenberg1,
  1. 1Department of Molecular Biology, Faculties of Science and Medicine, Radboud Institute for Molecular Life Sciences, Radboud University, 6500 HB Nijmegen, Netherlands.
  2. 2Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
  3. 3Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard School of Medicine, Boston, MA 02114, USA.
  4. 4Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.
  5. 5Department of Haematology, University of Cambridge, Cambridge, UK.
  6. 6National Health Service, Blood and Transplant Cambridge Centre, Cambridge Biomedical Campus, Cambridge CB0 2PT, UK.
  7. 7University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, Netherlands.
  8. 8Fourth Department of Internal Medicine, University of Athens, Medical School, 1 Rimini Street, 12462 Athens, Greece.
  1. Corresponding authors. E-mail: h.stunnenberg{at}ncmls.ru.nl (H.G.S.); mihai.netea{at}radboudumc.nl (M.G.N.); c.logie{at}ncmls.ru.nl (C.L.)
  1. * These authors contributed equally to this work.

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