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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

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Science  07 Nov 2014:
Vol. 346, Issue 6210, pp. 759-763
DOI: 10.1126/science.1254426

Article Information

vol. 346 no. 6210 759-763

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History: 
  • Received for publication April 4, 2014
  • Accepted for publication September 15, 2014
  • .

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Author Information

  1. James B. Munro1,*,,
  2. Jason Gorman2,
  3. Xiaochu Ma1,
  4. Zhou Zhou3,
  5. James Arthos4,
  6. Dennis R. Burton5,6,
  7. Wayne C. Koff7,
  8. Joel R. Courter8,,
  9. Amos B. Smith III8,
  10. Peter D. Kwong2,
  11. Scott C. Blanchard3,,
  12. Walther Mothes1,
  1. 1Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  2. 2Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  3. 3Department of Physiology and Biophysics, Weill Cornell Medical College of Cornell University, New York, NY 10021, USA.
  4. 4Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  5. 5Department of Immunology and Microbial Science, and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  6. 6Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02129, USA.
  7. 7International AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.
  8. 8Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA.
  1. Corresponding author. E-mail: walther.mothes{at}yale.edu (W.M.); scb2005{at}med.cornell.edu (S.C.B.); james.munro{at}tufts.edu (J.B.M.)
  • * Present address: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.

  • Present address: Incyte Corporation, Experimental Station, Wilmington, DE 19880, USA.

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