New support for ‘gay gene’

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Science  21 Nov 2014:
Vol. 346, Issue 6212, pp. 902
DOI: 10.1126/science.346.6212.902

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A new study of gay siblings revisits a finding that sparked social and scientific controversy more than 20 years ago. In a 1993 paper, molecular biologist Dean Hamer showed evidence that a region on the X chromosome is associated with male homosexuality, but several studies failed to confirm his finding. The largest replication effort so far, published online this week in Psychological Medicine, identifies the same region, known as Xq28. Not everyone is convinced by the evidence, however. And the genetic linkage technique the authors used can't offer what behavioral geneticists want most: a specific gene or genes that might subtly predispose a person to be gay.