An ancient defense system eliminates unfit cells from developing tissues during cell competition | Science

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Article Information

vol. 346 no. 6214

DOI:

https://doi.org/10.1126/science.1258236

PubMed:

Published By:

American Association for the Advancement of Science

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Online ISSN:

History:

Received for publication July 2, 2014
Accepted for publication October 31, 2014
.

Copyright & Usage:

Copyright © 2014, American Association for the Advancement of Science

Author Information

S. N. Meyer¹,*,
M. Amoyel²,*,†,
C. Bergantiños²,*,
C. de la Cova²,
C. Schertel¹,
K. Basler¹,‡,
L. A. Johnston²,‡

¹Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
²Department of Genetics and Development, Columbia University, New York, NY 10032, USA.

↵‡Corresponding author. E-mail: konrad.basler{at}imls.uzh.ch (K.B.); lj180{at}columbia.edu (L.A.J.)

↵* These authors contributed equally to this work.

↵† Present address: Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.

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Science: 346 (6214)

Science

Vol 346, Issue 6214
05 December 2014

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An ancient defense system eliminates unfit cells from developing tissues during cell competition

By S. N. Meyer, M. Amoyel, C. Bergantiños, C. de la Cova, C. Schertel, K. Basler, L. A. Johnston

Science05 Dec 2014

Components of the innate immune system are repurposed to eliminate weak cells during development. [Also see Perspective by Morata and Ballesteros-Arias]

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An ancient defense system eliminates unfit cells from developing tissues during cell competition

By S. N. Meyer, M. Amoyel, C. Bergantiños, C. de la Cova, C. Schertel, K. Basler, L. A. Johnston

Science05 Dec 2014

Components of the innate immune system are repurposed to eliminate weak cells during development. [Also see Perspective by Morata and Ballesteros-Arias]

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