Research Article

Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

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Science  20 Feb 2015:
Vol. 347, Issue 6224, pp. 842-847
DOI: 10.1126/science.1256022

Article Information

vol. 347 no. 6224 842-847

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History: 
  • Received for publication May 13, 2014
  • Accepted for publication January 2, 2015
  • .

Author Information

  1. Sanjay Premi1,
  2. Silvia Wallisch1,
  3. Camila M. Mano1,2,
  4. Adam B. Weiner1,*,
  5. Antonella Bacchiocchi3,
  6. Kazumasa Wakamatsu4,
  7. Etelvino J. H. Bechara2,5,,
  8. Ruth Halaban3,6,
  9. Thierry Douki7,,
  10. Douglas E. Brash1,6,
  1. 1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  2. 2Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05513-970 SP, Brazil.
  3. 3Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA.
  4. 4Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.
  5. 5Departamento de Ciências Exatas e da Terra, Universidade Federal de São Paulo, Diadema, São Paulo 09972-270 SP, Brazil.
  6. 6Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06520, USA.
  7. 7INAC/LCIB UMR-E3 CEA-UJF/Commissariat à l’Energie Atomique (CEA), 38054 Grenoble Cedex 9, France.
  1. Corresponding author. E-mail: douglas.brash{at}yale.edu
  1. These authors contributed equally to this work.

  • * Present address: Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA.

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