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Trapping a transition state in a computationally designed protein bottle

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Science  20 Feb 2015:
Vol. 347, Issue 6224, pp. 863-867
DOI: 10.1126/science.aaa2424

Article Information

vol. 347 no. 6224 863-867

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History: 
  • Received for publication November 6, 2014
  • Accepted for publication January 20, 2015
  • .

Author Information

  1. Aaron D. Pearson1,*,
  2. Jeremy H. Mills2,*,
  3. Yifan Song2,
  4. Fariborz Nasertorabi3,
  5. Gye Won Han3,
  6. David Baker2,4,
  7. Raymond C. Stevens3,
  8. Peter G. Schultz1,
  1. 1Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  3. 3Department of Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  4. 4Howard Hughes Medical Institute (HHMI), University of Washington, Seattle, WA 98195, USA.
  1. Corresponding author. E-mail: schultz{at}scripps.edu
  1. * These authors contributed equally to this work.

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