Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Amit Zeisel; Ana B. Muñoz-Manchado; Simone Codeluppi; Peter Lönnerberg; Gioele La Manno; Anna Juréus; Sueli Marques; Hermany Munguba; Liqun He; Christer Betsholtz; Charlotte Rolny; Gonçalo Castelo-Branco; Jens Hjerling-Leffler; Sten Linnarsson

doi:10.1126/science.aaa1934

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Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Amit Zeisel¹,*,
Ana B. Muñoz-Manchado¹,*,
Simone Codeluppi¹,
Peter Lönnerberg¹,
Gioele La Manno¹,
Anna Juréus¹,
Sueli Marques¹,
Hermany Munguba¹,
Liqun He²,
Christer Betsholtz²,³,
Charlotte Rolny⁴,
Gonçalo Castelo-Branco¹,
Jens Hjerling-Leffler¹,^†,
Sten Linnarsson¹,^†

¹Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.
²Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjölds väg 20, S-751 85 Uppsala, Sweden.
³Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.
⁴Department of Oncology-Pathology, Karolinska Institutet, S-171 76 Stockholm, Sweden.

↵†Corresponding author. E-mail: sten.linnarsson{at}ki.se (S.L.); jens.hjerling-leffler{at}ki.se (J.H.-L.)

↵* These authors contributed equally to this work.

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Science 06 Mar 2015:
Vol. 347, Issue 6226, pp. 1138-1142
DOI: 10.1126/science.aaa1934

Amit Zeisel

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Ana B. Muñoz-Manchado

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Simone Codeluppi

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Peter Lönnerberg

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Gioele La Manno

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Anna Juréus

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Sueli Marques

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Hermany Munguba

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Liqun He

2Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjölds väg 20, S-751 85 Uppsala, Sweden.

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Christer Betsholtz

2Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjölds väg 20, S-751 85 Uppsala, Sweden.

3Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Charlotte Rolny

4Department of Oncology-Pathology, Karolinska Institutet, S-171 76 Stockholm, Sweden.

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Gonçalo Castelo-Branco

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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Jens Hjerling-Leffler

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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For correspondence: sten.linnarsson@ki.se jens.hjerling-leffler@ki.se

Sten Linnarsson

1Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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For correspondence: sten.linnarsson@ki.se jens.hjerling-leffler@ki.se

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Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

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