13 March 2015
Vol 347, Issue 6227

About The Cover

Cover image expansion

COVER Models highlighting a simple and modular approach for making the complex secodaphnane natural product core. Synthesizing small molecules of such complexity has remained a customized and therefore slow and rarely automated process. Li et al. discovered that many different types of complex small molecules, including this one, can be made via automated assembly of a well-constrained set of readily available building blocks. See pages 1190 and 1221.
Photo: © Chris Brown/