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Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

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Science  17 Apr 2015:
Vol. 348, Issue 6232, pp. 340-343
DOI: 10.1126/science.1260384

Article Information

vol. 348 no. 6232 340-343

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History: 
  • Received for publication August 25, 2014
  • Accepted for publication March 12, 2015
  • .

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Author Information

  1. Pekka Katajisto1,2,3,4,*,,
  2. Julia Döhla4,
  3. Christine L. Chaffer1,
  4. Nalle Pentinmikko4,
  5. Nemanja Marjanovic1,2,
  6. Sharif Iqbal4,
  7. Roberto Zoncu1,2,3,
  8. Walter Chen1,2,3,
  9. Robert A. Weinberg1,2,
  10. David M. Sabatini1,2,3,5,6,*
  1. 1Whitehead Institute for Biomedical Research, Boston, MA 02142, USA.
  2. 2Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
  3. 3Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA.
  4. 4Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland.
  5. 5Broad Institute, Cambridge, MA 02142, USA.
  6. 6The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  1. *Corresponding author. E-mail: pekka.katajisto{at}helsinki.fi (P.K.); sabatini{at}wi.mit.edu (D.M.S.)
  • Present address: Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland.

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