Report
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
- Aashiq H. Kachroo1,
- Jon M. Laurent1,
- Christopher M. Yellman1,
- Austin G. Meyer1,2,
- Claus O. Wilke1,2,3,
- Edward M. Marcotte1,2,4,*
- 1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
- 2Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, TX 78712, USA.
- 3Department of Integrative Biology, University of Texas at Austin, Austin, TX 78712, USA.
- 4Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
- ↵*Corresponding author. E-mail: marcotte{at}icmb.utexas.edu
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Science 22 May 2015:
Vol. 348, Issue 6237, pp. 921-925
DOI: 10.1126/science.aaa0769
Vol. 348, Issue 6237, pp. 921-925
DOI: 10.1126/science.aaa0769
Aashiq H. Kachroo
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Jon M. Laurent
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Christopher M. Yellman
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Austin G. Meyer
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
2Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, TX 78712, USA.
Claus O. Wilke
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
2Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, TX 78712, USA.
3Department of Integrative Biology, University of Texas at Austin, Austin, TX 78712, USA.
Edward M. Marcotte
1Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
2Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, TX 78712, USA.
4Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
