Contents
Vol 348, Issue 6242
Contents
This Week in Science
Editorial
Editors' Choice
Podcasts
- Science Podcast: 26 June Show
On this week's show: Making metallic hydrogen and a roundup of daily news stories.
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Surviving Ebola survival
After recovering from Ebola, some patients are struggling with other health problems.
- An enhanced view of gene control
Chromosomal loops and domains help enhancers turn on genes.
- Breaking the light barrier
Trick for pushing more bits through optical fibers could ease looming “capacity crunch.”
- Tapping a nuclear test ban treasure-trove
Treaty chief offers academics surveillance data.
Feature
- The cancer test
A nonprofit's effort to replicate 50 top cancer papers is shaking up labs.
- Mission controller
How Alan Stern's tenacity, drive, and command got a NASA spacecraft to Pluto.
- Alan Stern's worldly ventures
Golden Spike and Uwingu are two of Stern's side efforts.
Working Life
Letters
Books et al.
- The living element
Radium played an important, but often forgotten, role in life sciences research in the early 20th century
Policy Forum
- Self-correction in science at work
Improve incentives to support research integrity
- Promoting an open research culture
Author guidelines for journals could help to promote transparency, openness, and reproducibility
Perspectives
- Ecological communities by design
Synthetic ecology requires knowledge of how microbial communities function
- Mother's littlest helpers
Breastmilk nourishes the microbes colonizing the neonatal intestinal tract
- Bearing down on hydrogen
Shockwaves are used to turn deuterium into a liquid metal.
- Who can cleave DMSP?
A DMSP lyase from an abundant marine eukaryote differs fundamentally from known bacterial enzymes.
- Topology, spin, and light
Evanescent solutions to Maxwell's equations correspond to surface modes with strong spin-momentum locking.
- A HUSH for transgene expression
A protein complex represses genes that insert into heterochromatin.
Association Affairs
Review
Research Article
- Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts
Identification of the committed cardiomyoblast that retains proliferative potential may inform cardiac regenerative therapeutics.
Reports
- Overcoming Kerr-induced capacity limit in optical fiber transmission
Digital back-propagation is used to mitigate light-induced nonlinear effects in optic fiber.
- Quantum spin Hall effect of light
A theoretical study reveals that quantum effects may manifest in classical optical experiments.
- Atomic gold–enabled three-dimensional lithography for silicon mesostructures
Diffusively patterned gold atoms are coated on silicon as a way to chemically pattern complex shapes.
- Direct observation of an abrupt insulator-to-metal transition in dense liquid deuterium
Magnetic compression drives an insulator-to-metal transition in dense liquid deuterium.
- Genomic determinants of coral heat tolerance across latitudes
In a warming world, existing variation in heat tolerance could help corals beat the heat.
- A 12 Å carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection
Large-scale pigment movement accompanies photoactivation of the orange carotenoid protein.
- Identification of the algal dimethyl sulfide–releasing enzyme: A missing link in the marine sulfur cycle
The dimethylsulfoniopropionate lyase of Emiliania huxleyi is part of a large enzyme family involved in the marine sulfur cycle.
- Possible artifacts of data biases in the recent global surface warming hiatus
Updated global surface temperature data do not support the notion of a global warming “hiatus.”
- A parvalbumin-positive excitatory visual pathway to trigger fear responses in mice
A newly identified subcortical pathway links visual inputs to the fear center of the brain.
- A Cas9–guide RNA complex preorganized for target DNA recognition
The guide RNA in the CRISPR-Cas immune/editing system is poised to initiate recognition of target DNA.
- Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
A haploid genetic screen in human cells identifies an epigenetic silencing complex that regulates heterochromatin formation.
- Factor-dependent processivity in human eIF4A DEAD-box helicase
A complex of three protein translation initiation factors is able to unwind messenger RNA continuously and directionally.
- Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
A transcription factor that controls both circadian rhythms and metabolism does so through different genomic mechanisms.
Technical Comments