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RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance

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Science  18 Sep 2015:
Vol. 349, Issue 6254, pp. 1351-1356
DOI: 10.1126/science.aab0917

Article Information

vol. 349 no. 6254 1351-1356

PubMed: 
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History: 
  • Received for publication March 10, 2015
  • Accepted for publication August 3, 2015

Author Information

  1. David T. Miyamoto1,2,*,
  2. Yu Zheng1,3,*,
  3. Ben S. Wittner1,4,
  4. Richard J. Lee1,4,
  5. Huili Zhu1,
  6. Katherine T. Broderick1,
  7. Rushil Desai1,
  8. Douglas B. Fox1,
  9. Brian W. Brannigan1,
  10. Julie Trautwein1,
  11. Kshitij S. Arora1,5,
  12. Niyati Desai1,5,
  13. Douglas M. Dahl1,6,
  14. Lecia V. Sequist1,4,
  15. Matthew R. Smith1,4,
  16. Ravi Kapur7,
  17. Chin-Lee Wu1,5,
  18. Toshi Shioda1,
  19. Sridhar Ramaswamy1,4,
  20. David T. Ting1,4,
  21. Mehmet Toner7,
  22. Shyamala Maheswaran1,8,,
  23. Daniel A. Haber1,3,4,
  1. 1Massachusetts General Cancer Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  2. 2Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  3. 3Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  4. 4Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  5. 5Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  6. 6Department of Urology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  7. 7Center for Bioengineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  8. 8Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  1. Corresponding author. E-mail: haber{at}helix.mgh.harvard.edu (D.H.); smaheswaran{at}mgh.harvard.edu (S.M.)
  1. * These authors contributed equally to this work.

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