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Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

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Science  25 Sep 2015:
Vol. 349, Issue 6255, pp. 1525-1529
DOI: 10.1126/science.aac9283

Article Information

vol. 349 no. 6255 1525-1529

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History: 
  • Received for publication June 30, 2015
  • Accepted for publication August 14, 2015
  • .

Author Information

  1. Francesco G. Mutti1,2,*,,
  2. Tanja Knaus2,,
  3. Nigel S. Scrutton2,
  4. Michael Breuer3,
  5. Nicholas J. Turner1,*
  1. 1School of Chemistry, University of Manchester, Manchester Institute of Biotechnology, Manchester M1 7DN, UK.
  2. 2Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK.
  3. 3BASF SE, White Biotechnology Research, GBW/B-A030, 67056 Ludwigshafen, Germany.
  1. *Corresponding author. E-mail: nicholas.turner{at}manchester.ac.uk (N.J.T.); f.mutti{at}uva.nl (F.G.M.)
  • Present address: Van ’t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, Netherlands.

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