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The 5300-year-old Helicobacter pylori genome of the Iceman
- Frank Maixner1,*,†,
- Ben Krause-Kyora2,†,
- Dmitrij Turaev3,†,
- Alexander Herbig4,5,†,
- Michael R. Hoopmann6,
- Janice L. Hallows6,
- Ulrike Kusebauch6,
- Eduard Egarter Vigl7,
- Peter Malfertheiner8,
- Francis Megraud9,
- Niall O’Sullivan1,
- Giovanna Cipollini1,
- Valentina Coia1,
- Marco Samadelli1,
- Lars Engstrand10,
- Bodo Linz11,
- Robert L. Moritz6,
- Rudolf Grimm12,
- Johannes Krause4,5,‡,
- Almut Nebel2,‡,
- Yoshan Moodley13,14,‡,
- Thomas Rattei3,‡,
- Albert Zink1,*,‡
- 1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
- 2Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstrasse 12, 24105 Kiel, Germany.
- 3CUBE–Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
- 4Institute for Archaeological Sciences, University of Tübingen, Rümelinstrasse 23, 72072 Tübingen, Germany.
- 5Max Planck Institute for the Science of Human History, Kahlaische Strasse 10, 07745 Jena, Germany.
- 6Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
- 7Scuola Superiore Sanitaria Provinciale “Claudiana,” Via Lorenz Böhler 13, 39100 Bolzano, Italy.
- 8Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto-von-Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany.
- 9Université de Bordeaux, Centre National de Référence des Helicobacters et Campylobacters and INSERM U853, 146 rue Léo Saignat, 33076 Bordeaux, France.
- 10Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 141 83 Stockholm, Sweden.
- 11Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA.
- 12Robert Mondavi Institute for Food Science, University of California, Davis, CA 95616, USA.
- 13Department of Zoology, University of Venda, Private Bag X5050, Thohoyandou 0950, Republic of South Africa.
- 14Department of Integrative Biology and Evolution, Konrad Lorenz Institute for Ethology, University of Veterinary Medicine Vienna, Savoyenstrasse 1a, 1160 Vienna, Austria.
- ↵*Corresponding author. E-mail: frank.maixner{at}eurac.edu (F.M.); albert.zink{at}eurac.edu (A.Z.)
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Science 08 Jan 2016:
Vol. 351, Issue 6269, pp. 162-165
DOI: 10.1126/science.aad2545
Vol. 351, Issue 6269, pp. 162-165
DOI: 10.1126/science.aad2545
Frank Maixner
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
Ben Krause-Kyora
2Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstrasse 12, 24105 Kiel, Germany.
Dmitrij Turaev
3CUBE–Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
Alexander Herbig
4Institute for Archaeological Sciences, University of Tübingen, Rümelinstrasse 23, 72072 Tübingen, Germany.
5Max Planck Institute for the Science of Human History, Kahlaische Strasse 10, 07745 Jena, Germany.
Michael R. Hoopmann
6Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
Janice L. Hallows
6Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
Ulrike Kusebauch
6Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
Eduard Egarter Vigl
7Scuola Superiore Sanitaria Provinciale “Claudiana,” Via Lorenz Böhler 13, 39100 Bolzano, Italy.
Peter Malfertheiner
8Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto-von-Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany.
Francis Megraud
9Université de Bordeaux, Centre National de Référence des Helicobacters et Campylobacters and INSERM U853, 146 rue Léo Saignat, 33076 Bordeaux, France.
Niall O’Sullivan
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
Giovanna Cipollini
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
Valentina Coia
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
Marco Samadelli
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
Lars Engstrand
10Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 141 83 Stockholm, Sweden.
Bodo Linz
11Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA.
Robert L. Moritz
6Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
Rudolf Grimm
12Robert Mondavi Institute for Food Science, University of California, Davis, CA 95616, USA.
Johannes Krause
4Institute for Archaeological Sciences, University of Tübingen, Rümelinstrasse 23, 72072 Tübingen, Germany.
5Max Planck Institute for the Science of Human History, Kahlaische Strasse 10, 07745 Jena, Germany.
Almut Nebel
2Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstrasse 12, 24105 Kiel, Germany.
Yoshan Moodley
13Department of Zoology, University of Venda, Private Bag X5050, Thohoyandou 0950, Republic of South Africa.
14Department of Integrative Biology and Evolution, Konrad Lorenz Institute for Ethology, University of Veterinary Medicine Vienna, Savoyenstrasse 1a, 1160 Vienna, Austria.
Thomas Rattei
3CUBE–Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
Albert Zink
1Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
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