Research Article

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

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Science  05 Feb 2016:
Vol. 351, Issue 6273, aad4395
DOI: 10.1126/science.aad4395

Article Information

vol. 351 no. 6273

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History: 
  • Received for publication September 15, 2015
  • Accepted for publication December 17, 2015
  • .

Author Information

  1. Hiroyuki Matsumura1,*,
  2. Yasuaki Mohri1,*,
  3. Nguyen Thanh Binh1,2,*,
  4. Hironobu Morinaga1,
  5. Makoto Fukuda1,
  6. Mayumi Ito3,
  7. Sotaro Kurata4,
  8. Jan Hoeijmakers5,
  9. Emi K. Nishimura1,
  1. 1Department of Stem Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
  2. 2Department of Stem Cell Medicine, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa 920-0934, Japan.
  3. 3Departments of Dermatology and Cell Biology, New York University School of Medicine, New York, NY, USA.
  4. 4Beppu Garden-Hill Clinic, Kurata Clinic, Beppu city, Oita 8740831, Japan.
  5. 5Department of Genetics, Cancer Genomics Center, Erasmus MC, Room Ee 722, Dr. Wytemaweg 80, 3015 CN Rotterdam, Netherlands.
  1. Corresponding author. E-mail: nishscm{at}tmd.ac.jp
  1. * These authors contributed equally to this work.

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