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Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

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Science  22 Apr 2016:
Vol. 352, Issue 6284, pp. 463-466
DOI: 10.1126/science.aaf3926

Article Information

vol. 352 no. 6284 463-466

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History: 
  • Received for publication February 3, 2016
  • Accepted for publication March 15, 2016
  • .

Author Information

  1. Padmini S. Pillai1,
  2. Ryan D. Molony1,
  3. Kimberly Martinod2,
  4. Huiping Dong1,
  5. Iris K. Pang1,
  6. Michal C. Tal1,*,
  7. Angel G. Solis1,
  8. Piotr Bielecki1,
  9. Subhasis Mohanty3,
  10. Mark Trentalange4,
  11. Robert J. Homer5,
  12. Richard A. Flavell1,8,
  13. Denisa D. Wagner2,
  14. Ruth R. Montgomery6,
  15. Albert C. Shaw3,
  16. Peter Staeheli7,
  17. Akiko Iwasaki1,8,
  1. 1Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
  2. 2Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.
  3. 3Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
  4. 4Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
  5. 5Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
  6. 6Section of Rheumatology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA.
  7. 7Institut für Medizinische Mikrobiologie und Hygiene, Institute of Virology, University Medical Center Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany.
  8. 8Howard Hughes Medical Institute, Yale School of Medicine, New Haven, CT 06520, USA.
  1. Corresponding author. Email: akiko.iwasaki{at}yale.edu
  • * Present address: Institute of Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford, CA 94305, USA.

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