Contents
19 August 2016
Vol 353, Issue 6301
Vol 353, Issue 6301
Special Issue
NEUROIMMUNOLOGY
Introduction to special issue
News
Reviews
Perspective
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- A debris-dammed lake threatens a flood
Engineers ponder fixes to Spirit Lake, bottled up 36 years ago by Mount St. Helens.
- Bones record demise of Andean state
Violent death surged as drought and political turmoil doomed the Wari.
- New polio cases in Nigeria spur massive response
Country's hopes for polio-free status are dashed.
- Mission possible: Rewriting the genetic code
A research team is making steady progress at overhauling a bacterium's genome.
- Chemists to get preprint server of their own
American Chemical Society launches ChemRxiv despite dubious precedents.
Feature
- Of mice and microbes
The zoo of bacteria and viruses each lab animal harbors may confound experiments.
- Tiger land
China's first national parks include a refuge for the world's largest cat.
Working Life
Letters
Books et al.
- Tough love for technology
A legal scholar probes how new technologies are raising risks, accentuating inequality, and affecting human nature
- Memory lane
An intimate portrait of a famous amnesiac is also a tale of personal grievances
Policy Forum
- Brazilian politics threaten environmental policies
The country's environmental licensing system is threatened
Perspectives
- The quest to burn fat, effortlessly and safely
An enzyme steps up to BAT as a potential mitochondrial uncoupler
- Diagnostics for Zika virus on the horizon
The immune response to Zika virus informs antibody-based diagnostics and therapeutics
- Thermalization in small quantum systems
A small closed quantum many-body system shows evidence of thermalization
- Fighting poverty with data
Machine learning algorithms measure and target poverty
- Now you see me too
Attaching chiral molecules to a chiral framework allows their molecular structures to be determined
Research Articles
- Microglia development follows a stepwise program to regulate brain homeostasis
The microbiota help regulate the development of active immune defense in the central nervous system of mice.
- Combining satellite imagery and machine learning to predict poverty
Satellites collect data that can be used to measure income and wealth.
- Quantum thermalization through entanglement in an isolated many-body system
Single-site microscopy of strings of rubidium atoms in an optical lattice shows thermalization on a local scale.
Reports
- Northward migration of the eastern Himalayan syntaxis revealed by OSL thermochronometry
Multi– optically stimulated luminescence thermochronometry of the Parlung Tsangpo knickpoint suggests headward migration as a response to tectonic uplift.
- Reverse osmosis molecular differentiation of organic liquids using carbon molecular sieve membranes
Carbon membranes efficiently separate similarly sized organic liquid molecules and isomers.
- Coordinative alignment of molecules in chiral metal-organic frameworks
The x-ray structural disorder of small molecules is reduced by covalent binding in a metal-organic framework.
- Integration of omic networks in a developmental atlas of maize
An atlas of the maize functional genome reveals patterns of developmental regulation within tissues for the transcriptome, proteome, and phosphoproteome.
- Design, synthesis, and testing toward a 57-codon genome
A computational and experimental framework for genome recoding enables synonymous codon replacement in Escherichia coli.
- Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
Cross-reactive antibody responses may pose a risk for disease on secondary infections with Dengue and/or Zika viruses.
- Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
A gene expression survey in patients with coronary artery disease reveals how genetic variation affects the risk of heart failure.
Technical Comments
About The Cover
COVER Resident immune cells in the brain, called microglia (purple), interact with neurons (yellow). The field of neuroimmunology has captivated a growing number of researchers as connections emerge between the body's defenses and the central nervous system. Immune cells in the brain play a role in many diseases but are also increasingly seen as central to normal brain development and function. See page 760.
Illustration: Valerie Altounian/Science
