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Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

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Science  30 Sep 2016:
Vol. 353, Issue 6307, pp. 1557-1560
DOI: 10.1126/science.aah3945

Article Information

vol. 353 no. 6307 1557-1560

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History: 
  • Received for publication June 20, 2016
  • Accepted for publication September 1, 2016
  • .

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Author Information

  1. Devin Sok1,2,3,*,
  2. Bryan Briney1,2,3,*,
  3. Joseph G. Jardine1,2,3,*,
  4. Daniel W. Kulp1,2,3,*,
  5. Sergey Menis1,2,3,
  6. Matthias Pauthner1,2,3,
  7. Andrew Wood4,
  8. E-Chiang Lee4,
  9. Khoa M. Le1,2,3,
  10. Meaghan Jones1,2,3,
  11. Alejandra Ramos1,2,3,
  12. Oleksandr Kalyuzhniy1,2,3,
  13. Yumiko Adachi1,2,3,
  14. Michael Kubitz1,2,3,
  15. Skye MacPherson1,2,3,
  16. Allan Bradley4,5,
  17. Glenn A. Friedrich4,
  18. William R. Schief1,2,3,6,,
  19. Dennis R. Burton1,2,3,6,
  1. 1Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Kymab Ltd, The Bennet Building (B930), Babraham Research Campus, Cambridge CB22 3AT, UK.
  5. 5Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  6. 6Ragon Institute of Massachusetts General Hospital (MGH), MIT, and Harvard, Cambridge, MA 02129, USA.
  1. Corresponding author. Email: burton{at}scripps.edu (D.R.B.); schief{at}scripps.edu (W.R.S.)
  1. * These authors contributed equally to this work.

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