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Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing
- Chun-Kan Chen1,
- Mario Blanco1,
- Constanza Jackson1,
- Erik Aznauryan1,
- Noah Ollikainen1,
- Christine Surka1,
- Amy Chow1,
- Andrea Cerase2,
- Patrick McDonel3,
- Mitchell Guttman1,*
- 1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
- 2European Molecular Biology Laboratory–Monterotondo, Via Ramarini 32, 00015 Monterotondo (RM), Italy.
- 3Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
- ↵*Corresponding author. Email: mguttman{at}caltech.edu
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Science 28 Oct 2016:
Vol. 354, Issue 6311, pp. 468-472
DOI: 10.1126/science.aae0047
Vol. 354, Issue 6311, pp. 468-472
DOI: 10.1126/science.aae0047
Chun-Kan Chen
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Mario Blanco
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Constanza Jackson
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Erik Aznauryan
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Noah Ollikainen
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Christine Surka
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Amy Chow
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Andrea Cerase
2European Molecular Biology Laboratory–Monterotondo, Via Ramarini 32, 00015 Monterotondo (RM), Italy.
Patrick McDonel
3Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Mitchell Guttman
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
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