Report

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

See allHide authors and affiliations

Science  31 Mar 2017:
Vol. 355, Issue 6332, pp. 1423-1427
DOI: 10.1126/science.aaf0683

Article Information

vol. 355 no. 6332 1423-1427

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 21, 2015
  • Resubmitted November 9, 2016
  • Accepted for publication January 6, 2017
  • .

Article Versions

Author Information

  1. Alice O. Kamphorst1,
  2. Andreas Wieland1,
  3. Tahseen Nasti1,
  4. Shu Yang1,2,*,
  5. Ruan Zhang3,
  6. Daniel L. Barber1,4,
  7. Bogumila T. Konieczny1,
  8. Candace Z. Daugherty1,
  9. Lydia Koenig5,
  10. Ke Yu5,
  11. Gabriel L. Sica6,
  12. Arlene H. Sharpe7,
  13. Gordon J. Freeman8,
  14. Bruce R. Blazar9,
  15. Laurence A. Turka3,
  16. Taofeek K. Owonikoko5,
  17. Rathi N. Pillai5,
  18. Suresh S. Ramalingam5,
  19. Koichi Araki1,
  20. Rafi Ahmed1,
  1. 1Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  2. 2Xiangya School of Medicine, Central South University, Changsha, Hunan Province, China, 410013.
  3. 3Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02144, USA.
  4. 4Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
  5. 5Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
  6. 6Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  7. 7Department of Microbiology and Immunobiology and Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Woman’s Hospital, Boston, MA 02115, USA.
  8. 8Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  9. 9Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
  1. Corresponding author. Email: rahmed{at}emory.edu
  • * Present address: Department of Neurology, Tianjin Medical University General Hospital, Tianjin 300052, China.

Altmetric

Article usage

Article usage: March 2017 to October 2019

AbstractFullPdf
Mar 20171448620524784
Apr 20171009011762657
May 201729884721160
Jun 20172096296624
Jul 20172155216493
Aug 20171535175397
Sep 20171528253466
Oct 20171351183329
Nov 20171162150320
Dec 2017780115228
Jan 2018843142320
Feb 2018727141229
Mar 2018704137246
Apr 2018567156365
May 2018437132270
Jun 2018384120221
Jul 2018292147183
Aug 201845945180
Sep 2018471298267
Oct 201888866357
Nov 2018461557420
Dec 2018471384197
Jan 2019231534250
Feb 2019521195197
Mar 2019531453245
Apr 2019621363206
May 2019521304270
Jun 2019361154227
Jul 2019441179172
Aug 2019461358156
Sep 2019521025187
Oct 20191332378

Navigate This Article