Personalized tumor vaccines keep cancer in check

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Science  14 Apr 2017:
Vol. 356, Issue 6334, pp. 122
DOI: 10.1126/science.356.6334.122

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  • Stimulation of endogenous stem cells in controlled eosinophilic syndrome against cancer
    • Andrey Ostanin, President, researcher, professor, Scientific Production System “Fertility & Ecology”

    Stimulation of endogenous stem cells in controlled eosinophilic syndrome against cancer

    Andrey L. Ostanin 1,*
    (1) Scientific Production System “Fertility & Ecology”
    * Email:

    1. Summary
    While analyzing the influence of immunocompetent cells to malignant neoplasms, we faced a natural deficiency of leukocyte granulocytes in majority of cancer patients. Scientific articles [1-4] prove the efficiency of eosinophil peroxidase toxic proteins in the fight against cancer. It is a natural anti-cancer defense mechanism, open to everyone. However, this mechanism often fails for several reasons. Immunity is trying to fix the problem, but production of immunocompetent cells lags behind the proliferation of cancer cells. There is an urgent need to stimulate endogenous stem cells, or rather to stimulate hematopoietic stem cells to produce more eosinophils, which proved their higher anti-cancer efficiency than T cells. It is also necessary to stimulate hematopoietic stem cells, because it is important to inhibit telomerase [5-11], i.e. to turn immortal cancer cells back into normal ones living by the laws of apoptosis. To effectively meet these challenges it was necessary to raise regenerative activity of stem cells, or hematopoietic stem cells, several-fold.
    2. Description of the mechanisms or pathways involved in the stimulation of endogenous stem cells
    To avoid...

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    Competing Interests: None declared.