Research Article

Self-organized Notch dynamics generate stereotyped sensory organ patterns in Drosophila

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Science  05 May 2017:
Vol. 356, Issue 6337, eaai7407
DOI: 10.1126/science.aai7407

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Self-organization for sensory brushes

Sensory hairs on the back of a fruit fly are lined up in neat rows. The orderliness of this arrangement has encouraged models based on organized specification of the hairs. Corson et al. now show that development is both less precise and more effective than that. They used mathematical modeling to recapitulate genetic effects as the developing epidermis becomes organized into enough rows and single lines of hairs. Their work suggests that the sensory field develops through self-organizing patterning that can adjust to the size of the epidermis.

Science, this issue p. eaai7407

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