Research Article

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

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Science  02 Jun 2017:
Vol. 356, Issue 6341, pp. 938-945
DOI: 10.1126/science.aai9383

Article Information

vol. 356 no. 6341 938-945

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History: 
  • Received for publication September 16, 2016
  • Resubmitted January 25, 2017
  • Accepted for publication April 13, 2017
  • .

Author Information

  1. Nichole R. Klatt1,*,,
  2. Ryan Cheu1,,
  3. Kenzie Birse2,3,,
  4. Alexander S. Zevin1,,
  5. Michelle Perner2,3,,
  6. Laura Noël-Romas2,3,,
  7. Anneke Grobler4,
  8. Garrett Westmacott5,
  9. Irene Y. Xie2,3,
  10. Jennifer Butler2,3,
  11. Leila Mansoor4,
  12. Lyle R. McKinnon3,4,
  13. Jo-Ann S. Passmore6,4,
  14. Quarraisha Abdool Karim4,7,
  15. Salim S. Abdool Karim4,7,
  16. Adam D. Burgener2,3,8,*,
  1. 1Department of Pharmaceutics, Washington National Primate Research Center, University of Washington, Seattle, WA, USA.
  2. 2National HIV and Retrovirology Labs, J.C. Wilt Infectious Diseases Research Centre, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
  3. 3Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
  4. 4Centre for the AIDS Program of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
  5. 5Mass Spectrometry and Proteomics Core Facility, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
  6. 6Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town and National Health Laboratory Service, Cape Town, South Africa.
  7. 7Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, USA.
  8. 8Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
  1. *Corresponding author. Email: adam.burgener{at}umanitoba.ca (A.D.B.); klattnr{at}uw.edu (N.R.K.)
  1. These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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