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PAF1 regulation of promoter-proximal pause release via enhancer activation

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Science  22 Sep 2017:
Vol. 357, Issue 6357, pp. 1294-1298
DOI: 10.1126/science.aan3269

Article Information

vol. 357 no. 6357 1294-1298

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History: 
  • Received for publication March 28, 2017
  • Accepted for publication August 22, 2017
  • .

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Author Information

  1. Fei Xavier Chen1,
  2. Peng Xie2,
  3. Clayton K. Collings1,
  4. Kaixiang Cao1,
  5. Yuki Aoi1,
  6. Stacy A. Marshall1,
  7. Emily J. Rendleman1,
  8. Michal Ugarenko1,
  9. Patrick A. Ozark1,
  10. Anda Zhang3,
  11. Ramin Shiekhattar3,
  12. Edwin R. Smith1,
  13. Michael Q. Zhang2,4,
  14. Ali Shilatifard1,5,*
  1. 1Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  2. 2Department of Biological Sciences, Center for Systems Biology, University of Texas at Dallas, Richardson, TX 75080, USA.
  3. 3Sylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  4. 4MOE Key Laboratory of Bioinformatics, Bioinformatics Division and Center for Synthetic & Systems Biology, TNLIST, Tsinghua University, Beijing 100084, China.
  5. 5Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  1. *Corresponding author. Email: ash{at}northwestern.edu

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