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Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

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Science  22 Sep 2017:
Vol. 357, Issue 6357, pp. 1303-1307
DOI: 10.1126/science.aan4187

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vol. 357 no. 6357 1303-1307

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History: 
  • Received for publication April 10, 2017
  • Accepted for publication August 3, 2017
  • .

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Author Information

  1. Dong Niu1,2,*,
  2. Hong-Jiang Wei3,4,*,
  3. Lin Lin5,*,
  4. Haydy George1,*,
  5. Tao Wang1,*,
  6. I-Hsiu Lee1,*,
  7. Hong-Ye Zhao3,
  8. Yong Wang6,
  9. Yinan Kan1,
  10. Ellen Shrock7,
  11. Emal Lesha1,
  12. Gang Wang1,
  13. Yonglun Luo5,
  14. Yubo Qing3,4,
  15. Deling Jiao3,4,
  16. Heng Zhao3,4,
  17. Xiaoyang Zhou6,
  18. Shouqi Wang8,
  19. Hong Wei6,
  20. Marc Güell1,,
  21. George M. Church1,7,9,,
  22. Luhan Yang1,,
  1. 1eGenesis, Cambridge, MA 02139, USA.
  2. 2College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
  3. 3State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.
  4. 4College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
  5. 5Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
  6. 6Department of Laboratory Animal Science, College of Basic Medical Sciences, Third Military Medical University, Chongqing, 400038, China.
  7. 7Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  8. 8Research Institute of Shenzhen Jinxinnong Technology, Shenzhen 518106, China.
  9. 9Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA 02138, USA.
  1. Corresponding author. Email: luhan.yang{at}egenesisbio.com
  1. * These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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