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A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

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Science  17 Nov 2017:
Vol. 358, Issue 6365, pp. 933-936
DOI: 10.1126/science.aam7120

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vol. 358 no. 6365 933-936

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History: 
  • Received for publication January 18, 2017
  • Resubmitted May 19, 2017
  • Accepted for publication September 20, 2017
  • .

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Author Information

  1. Ling Yuan1,2,*,
  2. Xing-Yao Huang3,*,
  3. Zhong-Yu Liu3,*,
  4. Feng Zhang1,2,*,
  5. Xing-Liang Zhu1,2,*,
  6. Jiu-Yang Yu3,*,
  7. Xue Ji3,
  8. Yan-Peng Xu3,
  9. Guanghui Li1,2,
  10. Cui Li1,2,
  11. Hong-Jiang Wang3,
  12. Yong-Qiang Deng3,
  13. Menghua Wu4,
  14. Meng-Li Cheng3,5,
  15. Qing Ye3,
  16. Dong-Yang Xie3,5,
  17. Xiao-Feng Li3,
  18. Xiangxi Wang6,
  19. Weifeng Shi7,
  20. Baoyang Hu4,
  21. Pei-Yong Shi8,
  22. Zhiheng Xu1,2,9,,
  23. Cheng-Feng Qin3,
  1. 1State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.
  2. 2University of CAS, Beijing 100101, China.
  3. 3Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
  4. 4State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, CAS, Beijing 100101, China.
  5. 5Graduate School, Anhui Medical University, Hefei 230032, China.
  6. 6National Laboratory of Macromolecules, Institute of Biophysics, CAS, Beijing 100101, China.
  7. 7Shandong Universities Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases, Taishan Medical College, Taian 271000, China.
  8. 8Department of Biochemistry and Molecular Biology and Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
  9. 9Parkinson’s Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China.
  1. Corresponding author. Email: qincf{at}bmi.ac.cn (C.-F.Q.); zhxu{at}genetics.ac.cn (Z.X.)
  1. * These authors contributed equally to this work.

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