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Defective cholesterol clearance limits remyelination in the aged central nervous system

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Science  09 Feb 2018:
Vol. 359, Issue 6376, pp. 684-688
DOI: 10.1126/science.aan4183

Article Information

vol. 359 no. 6376 684-688

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History: 
  • Received for publication April 10, 2017
  • Resubmitted November 5, 2017
  • Accepted for publication December 11, 2017

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Author Information

  1. Ludovico Cantuti-Castelvetri1,2,3,4,*,
  2. Dirk Fitzner1,5,*,
  3. Mar Bosch-Queralt1,2,3,4,
  4. Marie-Theres Weil1,6,
  5. Minhui Su1,2,3,4,
  6. Paromita Sen1,
  7. Torben Ruhwedel7,
  8. Miso Mitkovski8,
  9. George Trendelenburg5,
  10. Dieter Lütjohann9,
  11. Wiebke Möbius6,7,
  12. Mikael Simons1,2,3,4,
  1. 1Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
  2. 2Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
  3. 3Institute of Neuronal Cell Biology, Technical University Munich, 80805 Munich, Germany.
  4. 4German Center for Neurodegenerative Disease (DZNE), 81377 Munich, Germany.
  5. 5Department of Neurology, University of Göttingen Medical Center, 37075 Göttingen, Germany.
  6. 6Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), 37075 Göttingen, Germany.
  7. 7Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
  8. 8Light Microscopy Facility, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
  9. 9Institute for Clinical Chemistry and Clinical Pharmacology, University of Bonn, 53127 Bonn, Germany.
  1. Corresponding author. Email: msimons{at}gwdg.de
  1. * These authors contributed equally to this work.

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Jan 2018113568131201
Feb 201880947181436
Mar 20181002199392
Apr 2018683147233
May 2018572114162
Jun 201850483145
Jul 20184029485
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Sep 2018245170104
Oct 2018299173104
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Dec 2018243157101
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Feb 201983280100
Mar 20192037191
Apr 201922332150
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Jun 2019611358

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