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Science  23 Feb 2018:
Vol. 359, Issue 6378, pp. 926-930
DOI: 10.1126/science.aar3247

Article Information

vol. 359 no. 6378 926-930

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History: 
  • Received for publication October 31, 2017
  • Accepted for publication January 8, 2018
  • .

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Author Information

  1. Joshua D. Cohen1,2,3,4,5,
  2. Lu Li6,
  3. Yuxuan Wang1,2,3,4,
  4. Christopher Thoburn3,
  5. Bahman Afsari7,
  6. Ludmila Danilova7,
  7. Christopher Douville1,2,3,4,
  8. Ammar A. Javed8,
  9. Fay Wong1,3,4,
  10. Austin Mattox1,2,3,4,
  11. Ralph H. Hruban3,4,9,
  12. Christopher L. Wolfgang8,
  13. Michael G. Goggins3,4,9,10,11,
  14. Marco Dal Molin4,
  15. Tian-Li Wang3,9,
  16. Richard Roden3,9,
  17. Alison P. Klein3,4,12,
  18. Janine Ptak1,2,3,4,
  19. Lisa Dobbyn1,3,4,
  20. Joy Schaefer1,3,4,
  21. Natalie Silliman1,2,3,4,
  22. Maria Popoli1,3,4,
  23. Joshua T. Vogelstein13,
  24. James D. Browne14,
  25. Robert E. Schoen15,16,
  26. Randall E. Brand15,
  27. Jeanne Tie17,18,19,20,
  28. Peter Gibbs17,18,19,20,
  29. Hui-Li Wong17,
  30. Aaron S. Mansfield21,
  31. Jin Jen22,
  32. Samir M. Hanash23,
  33. Massimo Falconi24,
  34. Peter J. Allen25,
  35. Shibin Zhou1,3,4,
  36. Chetan Bettegowda1,3,4,
  37. Luis A. Diaz Jr.1,3,4,*,
  38. Cristian Tomasetti3,6,7,,
  39. Kenneth W. Kinzler1,3,4,,
  40. Bert Vogelstein1,2,3,4,,
  41. Anne Marie Lennon3,4,8,10,11,,
  42. Nickolas Papadopoulos1,3,4,
  1. 1Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  2. 2Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  3. 3Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  4. 4Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  5. 5Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  6. 6Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  7. 7Division of Biostatistics and Bioinformatics, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  8. 8Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  9. 9Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  10. 10Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  11. 11Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  12. 12Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  13. 13Institute for Computational Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  14. 14Department of Computer Science, Johns Hopkins University Whiting School of Engineering, Baltimore, MD 21218, USA.
  15. 15Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  16. 16Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  17. 17Division of Systems Biology and Personalized Medicine, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3021, Australia.
  18. 18Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.
  19. 19Department of Medical Oncology, Western Health, Melbourne, VIC 3021, Australia.
  20. 20Department of Medical Oncology, Peter MacCallum Cancer Center, Melbourne, VIC 3000, Australia.
  21. 21Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.
  22. 22Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55902, USA.
  23. 23Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  24. 24Division of Pancreatic Surgery, Department of Surgery, San Raffaele Scientific Institute Research Hospital, 20132 Milan, Italy.
  25. 25Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  1. Corresponding author. Email: ctomasetti{at}jhu.edu (C.T.); amlennon{at}jhmi.edu (A.M.L.); kinzlke{at}jhmi.edu (K.W.K.); bertvog{at}gmail.com (B.V.); npapado1{at}jhmi.edu (N.P.)

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