Research Article

The transcriptional landscape of polyploid wheat

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Science  17 Aug 2018:
Vol. 361, Issue 6403, eaar6089
DOI: 10.1126/science.aar6089

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Vertical Tabs

  • Wheat transcriptome and its interaction with a mycotoxigenic fungus Fusarium graminearum - A much required study
    • Lalit Laxman Kharbikar, Scientist (Biotechnology), ICAR - National Institute of Biotic Stress Management, Raipur, India.
    • Other Contributors:
      • Arti S. Shanware, Director, Rajiv Gandhi Biotechnology Centre, RTM Nagpur University, Nagpur, India.
      • Shweta Kishor Nandanwar, Freelance Science Writer

    Dear Authors,
    Building resistance in the host is the perfect means of controlling diseases in crops. In many crops, resistance is governed by several genes in RNA interference (RNAi) pathways which are regulated by microRNAs (miRNAs). A number of miRNAs have been identified and characterized in wheat. Few researchers have also characterized the miRNAs in wheat in response to fungal pathogens including Fusarium. In this context, understanding the host RNAi pathways should enable us to build disease resistance in hosts. However, the host RNAi pathways may be suppressed by the fungal microRNA-like RNAs (milRNAs) which have not been characterized so far in an economically important mycotoxigenic pathogen, F. graminearum.
    Hence, there is a need for identification of milRNAs in F. graminearum and investigation of their interaction with genes annotated by your team in the transcriptional landscape of polyploid wheat. Significant progress made in the knowledge of microRNAs (miRNAs), advancements in bioinformatics tools and readily available rich genomic databases can be utilized for this purpose.

    Competing Interests: None declared.

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