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A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme

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Science  14 Sep 2018:
Vol. 361, Issue 6407, pp. 1098-1101
DOI: 10.1126/science.aat8474

Article Information

vol. 361 no. 6407 1098-1101

PubMed: 
Print ISSN: 
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History: 
  • Received for publication April 11, 2018
  • Accepted for publication July 25, 2018
  • .

Author Information

  1. Evan N. Mirts1,
  2. Igor D. Petrik2,
  3. Parisa Hosseinzadeh3,
  4. Mark J. Nilges4,
  5. Yi Lu1,2,3,5,6,7,*
  1. 1Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  2. 2Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  3. 3Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  4. 4School of Chemical Sciences Electron Paramagnetic Resonance Lab, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  5. 5Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  6. 6DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  7. 7Pacific Northwest National Laboratory, Richland, WA 99352, USA.
  1. *Corresponding author. Email: yi-lu{at}illinois.edu

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