Contents
Vol 362, Issue 6412
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Scientists who beat the odds seek victory in November
Candidates, all Democrats, learned in the primaries that a science background by itself does not sway voters.
- Scientists, environmentalists brace for Brazil's right turn
Country's likely next president promises R&D investment but favors development over climate and biodiversity.
- NASA's asteroid explorer Dawn soon to go dark
Mission was first to orbit two planetary bodies, Vesta and Ceres.
- China narrows U.S. lead in R&D spending
But lagging support for basic research may hinder ambitions to become a science superpower.
- Outbreaks of poliolike disease pose a puzzle
An enterovirus may cause sudden paralysis in children, but proof is elusive.
Feature
- Toxin or treatment?
Ingesting small doses of peanut products guards against allergic reactions—but an undercurrent of anxiety persists.
Working Life
Letters
Books et al.
- The familiar politics of the final frontier
Earth's economic woes haunt the first lunar colony in a fictional near future
- Recognizing the role of skilled immigration
A scholar examines the rewards and shortcomings of global talent in the United States
Policy Forum
- Endangered species recovery: A resource allocation problem
Explicit articulation of values and objectives is critical
Perspectives
- Well-being in metrics and policy
Well-being metrics provide key insights for economic and environmental sustainability
- Computational complexity, step by step
For certain linear algebra tasks, quantum circuits are proven to outperform classical ones
- Supracellular contractions propel migration
Cytoskeletal cords connecting cells at the back of cell groups enable directional migration
- Toward human egg-like cells in vitro
Human precursor egg-like cells are produced in mouse ovary organoids to study infertility
- A friendly danger
Immune cell receptor DNGR-1 limits inflammatory tissue damage
- Earth's soft heart
A modern seismological method raises questions about the properties of Earth's inner core
Research Articles
- Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1
Structures provide insight into how voltage-gated sodium channels function and how they can be inhibited.
- Structural basis for the modulation of voltage-gated sodium channels by animal toxins
Structures provide insight into how voltage-gated sodium channels function and how they can be inhibited.
- Relationship of gender differences in preferences to economic development and gender equality
A global investigation suggests that access to higher levels of material and social resources promotes gender-specific preferences.
Reviews
Reports
- Quantum advantage with shallow circuits
Parallel quantum circuits outperform classical counterparts at solving certain linear algebra problems.
- Chiral Lewis acids integrated with single-walled carbon nanotubes for asymmetric catalysis in water
A combination of surfactants and supporting single-walled carbon nanotubes render chiral nickel catalysts effective in water.
- Hierarchically porous polymer coatings for highly efficient passive daytime radiative cooling
Tuning the air-filled void distribution in a polymer can produce a film with excellent radiative cooling properties.
- Aptamer–field-effect transistors overcome Debye length limitations for small-molecule sensing
Large conformational changes induced in charged DNA stem-loop receptors can be sensed in high–ionic strength solutions.
- A family of finite-temperature electronic phase transitions in graphene multilayers
Stacks of graphene up to seven layers thick show a strong dependence of the critical temperature on the number of layers.
- Shear properties of Earth’s inner core constrained by a detection of J waves in global correlation wavefield
The detection of shear waves through Earth’s inner core confirms that it is solid but soft.
- Evidence for Majorana bound states in an iron-based superconductor
Scanning tunneling spectroscopy reveals signatures of Majorana bound states on the surface of FeTe1−xSex.
- Hyperfine interaction of individual atoms on a surface
Atom manipulation and spin sensing with scanning tunneling microscopy reveal details underlying hyperfine interactions.
- Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis
A rear engine drives collective chemotaxis in migrating Xenopus and zebrafish embryonic stem cells.
- The opium poppy genome and morphinan production
The opium poppy genome reveals gene duplication, rearrangement, and fusion events that led to morphine production.
- Realizing private and practical pharmacological collaboration
A computational protocol enables private pharmacological data to be securely combined.
- DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment
A damage-sensing receptor hits the brakes to control the extent of tissue damage during infection, injury, and inflammation.
- Generation of human oogonia from induced pluripotent stem cells in vitro
Human primordial germ cell–like cells differentiate into oogonia in xenogeneic reconstituted ovaries in vitro.
Technical Comments
Erratum
About The Cover

COVER Between 1 and 2% of people in the United States are allergic to peanuts. A new treatment strategy exposes affected children to peanuts or peanut proteins in hopes of desensitizing their immune system. This approach has gained popularity as doctors in private practice offer it and two commercial products are nearing potential approval. But it also comes with risks and uncertainties. See page 278.
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