Books et al.Structural Biology

The ribosome, revealed

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Science  23 Nov 2018:
Vol. 362, Issue 6417, pp. 901
DOI: 10.1126/science.aav4624

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Summary

By the late 1970s, the structure of DNA had already been "solved," and the genetic code already "cracked," leading many to conclude that there was little left to learn in this arena. However, the quest to understand the process by which the ribosome converts genetic information into proteins was still in its infancy. In Gene Machine, Venki Ramakrishnan provides a frank behind-the-scenes account of the 30-year race to solve the structure of the ribosome that earned him a share of the Nobel Prize in chemistry in 2009.

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