Essays on Science and SocietyTranslational Medicine

Microbiome dynamics in obesity

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Science  23 Nov 2018:
Vol. 362, Issue 6417, pp. 903-904
DOI: 10.1126/science.aav6870


The prevalence of obesity has increased at an astounding rate over the past decades. More than 44% of the global population is estimated to be overweight, and more than 300 million individuals are affected by morbid adiposity (1). Obesity is a major risk factor for a number of co-occurring diseases, including type II diabetes mellitus, nonalcoholic fatty liver disease, and ischemic cardiovascular disease (2). Thus, the obesity pandemic has far-reaching consequences on life expectancy, quality of life, and health-care costs.

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