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Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode
- View ORCID ProfileChangwoo Seo1,2,*,
- View ORCID ProfileAkash Guru1,2,*,
- View ORCID ProfileMichelle Jin1,†,
- Brendan Ito1,
- View ORCID ProfileBrianna J. Sleezer1,
- View ORCID ProfileYi-Yun Ho1,2,
- Elias Wang1,‡,
- View ORCID ProfileChristina Boada1,§,
- View ORCID ProfileNicholas A. Krupa1,
- View ORCID ProfileDurgaprasad S. Kullakanda1,
- View ORCID ProfileCynthia X. Shen1,
- View ORCID ProfileMelissa R. Warden1,2¶
- 1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
- 2Cornell Neurotech, Cornell University, Ithaca, NY 14853, USA.
- ↵¶Corresponding author. Email: mrwarden{at}cornell.edu
↵* These authors contributed equally to this work.
↵† Present address: Neurobiology of Relapse Section, National Institute on Drug Abuse (NIDA) Intramural Research Program, Baltimore, MD 21224, USA.
↵‡ Present address: Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
↵§ Present address: School of Medicine, New York University, New York, NY 10016, USA.
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Science 01 Feb 2019:
Vol. 363, Issue 6426, pp. 538-542
DOI: 10.1126/science.aau8722
Vol. 363, Issue 6426, pp. 538-542
DOI: 10.1126/science.aau8722
Changwoo Seo
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
2Cornell Neurotech, Cornell University, Ithaca, NY 14853, USA.
Akash Guru
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
2Cornell Neurotech, Cornell University, Ithaca, NY 14853, USA.
Michelle Jin
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Brendan Ito
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Brianna J. Sleezer
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Yi-Yun Ho
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
2Cornell Neurotech, Cornell University, Ithaca, NY 14853, USA.
Elias Wang
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Christina Boada
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Nicholas A. Krupa
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Durgaprasad S. Kullakanda
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Cynthia X. Shen
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Melissa R. Warden
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
2Cornell Neurotech, Cornell University, Ithaca, NY 14853, USA.