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An ingestible self-orienting system for oral delivery of macromolecules

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Science  08 Feb 2019:
Vol. 363, Issue 6427, pp. 611-615
DOI: 10.1126/science.aau2277

Article Information

vol. 363 no. 6427 611-615

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History: 
  • Received for publication May 21, 2018
  • Accepted for publication January 4, 2019
  • .

Author Information

  1. Alex Abramson1,
  2. Ester Caffarel-Salvador1,2,
  3. Minsoo Khang1,
  4. David Dellal2,
  5. David Silverstein1,
  6. Yuan Gao1,
  7. Morten Revsgaard Frederiksen3,
  8. Andreas Vegge3,
  9. František Hubálek3,
  10. Jorrit J. Water3,
  11. Anders V. Friderichsen3,
  12. Johannes Fels3,
  13. Rikke Kaae Kirk3,
  14. Cody Cleveland1,3,
  15. Joy Collins1,
  16. Siddartha Tamang1,
  17. Alison Hayward1,4,
  18. Tomas Landh3,
  19. Stephen T. Buckley3,
  20. Niclas Roxhed1,5,
  21. Ulrik Rahbek3,
  22. Robert Langer1,2,6,*,
  23. Giovanni Traverso1,7,8,*
  1. 1Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  2. 2Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  3. 3Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Copenhagen, Denmark.
  4. 4Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  5. 5Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden.
  6. 6Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  7. 7Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  8. 8Division of Gastroenterology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  1. *Corresponding author. Email: rlanger{at}mit.edu (R.L.); ctraverso{at}bwh.harvard.edu (G.T.)

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