Research Article

Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

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Science  22 Mar 2019:
Vol. 363, Issue 6433, eaar7486
DOI: 10.1126/science.aar7486

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Rapid response to tissue damage

Damaged plants are susceptible to microbial attack. In response to physical damage, plants proactively generate signal peptides to activate their immune systems. Hander et al. examined wound responses in the model plant Arabidopsis thaliana. They identified a metacaspase that releases an immunomodulatory signal peptide from its precursor form within 30 seconds of the damage. The metacaspase itself was activated by a burst of calcium released by tissue damage.

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