Evidence for hormonal control of heart regenerative capacity during endothermy acquisition

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Science  12 Apr 2019:
Vol. 364, Issue 6436, pp. 184-188
DOI: 10.1126/science.aar2038

Article Information

vol. 364 no. 6436 184-188

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  • Received for publication October 13, 2017
  • Resubmitted November 15, 2018
  • Accepted for publication February 21, 2019

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Author Information

  1. Kentaro Hirose1,2,*,
  2. Alexander Y. Payumo1,2,*,
  3. Stephen Cutie1,2,
  4. Alison Hoang1,2,
  5. Hao Zhang3,
  6. Romain Guyot4,
  7. Dominic Lunn1,2,
  8. Rachel B. Bigley1,2,
  9. Hongyao Yu5,
  10. Jiajia Wang5,
  11. Megan Smith6,
  12. Ellen Gillett7,
  13. Sandra E. Muroy8,
  14. Tobias Schmid9,
  15. Emily Wilson3,
  16. Kenneth A. Field10,
  17. DeeAnn M. Reeder10,
  18. Malcom Maden11,
  19. Michael M. Yartsev9,
  20. Michael J. Wolfgang12,
  21. Frank Grützner7,
  22. Thomas S. Scanlan13,
  23. Luke I. Szweda14,
  24. Rochelle Buffenstein6,
  25. Guang Hu5,
  26. Frederic Flamant4,
  27. Jeffrey E. Olgin1,3,
  28. Guo N. Huang1,2,
  1. 1Cardiovascular Research Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA.
  2. 2Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94158, USA.
  3. 3Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94158, USA.
  4. 4Department of Internal Medicine, Institut de Génomique Fonctionnelle de Lyon, Institut National de la Recherche Agronomique, Université Lyon 1, CNRS, École Normale Superieure de Lyon, 69 007 France.
  5. 5Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
  6. 6Calico Life Sciences, 1170 Veterans Boulevard, South San Francisco, CA 94080, USA.
  7. 7School of Biological Sciences, University of Adelaide, South Australia, Adelaide 5005, Australia.
  8. 8Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94708, USA.
  9. 9Helen Wills Neuroscience Institute and Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94708, USA.
  10. 10Department of Biology, Bucknell University, Lewisburg, PA 17837, USA.
  11. 11Department of Biology and UF Genetics Institute, University of Florida, Gainesville, FL 32611, USA.
  12. 12Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  13. 13Department of Physiology and Pharmacology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
  14. 14Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8573, USA.
  1. Corresponding author. Email: guo.huang{at}
  1. * These authors contributed equally to this work.


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Article usage: March 2019 to May 2019

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Apr 2019665120771095
May 2019706455247