Research Article

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

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Science  12 Apr 2019:
Vol. 364, Issue 6436, eaat8078
DOI: 10.1126/science.aat8078

Article Information

vol. 364 no. 6436

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  • Received for publication May 7, 2018
  • Accepted for publication February 18, 2019

Author Information

  1. R. N. Moda-Sava1,*,
  2. M. H. Murdock1,*,
  3. P. K. Parekh1,*,
  4. R. N. Fetcho1,
  5. B. S. Huang1,
  6. T. N. Huynh1,
  7. J. Witztum1,
  8. D. C. Shaver1,
  9. D. L. Rosenthal1,
  10. E. J. Alway1,
  11. K. Lopez1,
  12. Y. Meng1,
  13. L. Nellissen1,
  14. L. Grosenick1,2,
  15. T. A. Milner1,
  16. K. Deisseroth2,
  17. H. Bito3,
  18. H. Kasai4,5,
  19. C. Liston1,
  1. 1Brain and Mind Research Institute, Department of Psychiatry, and Sackler Institute for Developmental Psychobiology, Weill Cornell Medicine, New York, NY 10021, USA.
  2. 2Departments of Bioengineering and of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
  3. 3Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
  4. 4Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
  5. 5International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
  1. Corresponding author. Email: col2004{at}
  1. * These authors contributed equally to this work.


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