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Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq

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Science  19 Apr 2019:
Vol. 364, Issue 6437, pp. 286-289
DOI: 10.1126/science.aav9023

Article Information

vol. 364 no. 6437 286-289

PubMed: 
Print ISSN: 
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History: 
  • Received for publication November 8, 2018
  • Accepted for publication February 23, 2019
  • .

Author Information

  1. Beeke Wienert1,2,3,*,
  2. Stacia K. Wyman1,*,
  3. Christopher D. Richardson1,2,
  4. Charles D. Yeh1,2,,
  5. Pinar Akcakaya4,
  6. Michelle J. Porritt4,
  7. Michaela Morlock4,
  8. Jonathan T. Vu1,
  9. Katelynn R. Kazane1,2,
  10. Hannah L. Watry1,3,
  11. Luke M. Judge3,5,
  12. Bruce R. Conklin3,6,
  13. Marcello Maresca4,
  14. Jacob E. Corn1,2,,
  1. 1Innovative Genomics Institute, University of California Berkeley, Berkeley, CA 94704, USA.
  2. 2Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720, USA.
  3. 3Gladstone Institutes, San Francisco, CA 94158, USA.
  4. 4Discovery Biology, AstraZeneca, 43150 Gothenburg, Sweden.
  5. 5Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA.
  6. 6Departments of Medicine, Ophthalmology, and Pharmacology, University of California San Francisco, San Francisco, California 94143, USA.
  1. Corresponding author. Email: jacob.corn{at}biol.ethz.ch
  1. * These authors contributed equally to this work.

  • Present address: Department of Biology, ETH Zurich 8092, Switzerland.

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Article usage: April 2019 to December 2019

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May 201915971546850
Jun 2019744568298
Jul 2019478409247
Aug 2019592592251
Sep 2019494375166
Oct 2019480366185
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