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Photoexcitation of flavoenzymes enables a stereoselective radical cyclization
- View ORCID ProfileKyle F. Biegasiewicz1,*,
- View ORCID ProfileSimon J. Cooper1,*,
- View ORCID ProfileXin Gao1,*,
- View ORCID ProfileDaniel G. Oblinsky1,
- Ji Hye Kim1,
- View ORCID ProfileSamuel E. Garfinkle1,
- Leo A. Joyce2,
- Braddock A. Sandoval1,
- Gregory D. Scholes1,
- View ORCID ProfileTodd K. Hyster1,†
- 1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
- 2Department of Process Research and Development, Merck, Rahway, NJ 07065, USA.
- ↵†Corresponding author. Email: thyster{at}princeton.edu
↵* These authors contributed equally to this work.
See allHide authors and affiliations
Science 21 Jun 2019:
Vol. 364, Issue 6446, pp. 1166-1169
DOI: 10.1126/science.aaw1143
Vol. 364, Issue 6446, pp. 1166-1169
DOI: 10.1126/science.aaw1143
Kyle F. Biegasiewicz
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Simon J. Cooper
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Xin Gao
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Daniel G. Oblinsky
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Ji Hye Kim
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Samuel E. Garfinkle
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Leo A. Joyce
2Department of Process Research and Development, Merck, Rahway, NJ 07065, USA.
Braddock A. Sandoval
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Gregory D. Scholes
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Todd K. Hyster
1Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
