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Direct arene C–H fluorination with 18F− via organic photoredox catalysis
- View ORCID ProfileWei Chen1,*,
- View ORCID ProfileZeng Huang1,*,
- View ORCID ProfileNicholas E. S. Tay2,*,
- Benjamin Giglio1,
- Mengzhe Wang1,
- View ORCID ProfileHui Wang1,
- View ORCID ProfileZhanhong Wu1,
- View ORCID ProfileDavid A. Nicewicz2,†,
- View ORCID ProfileZibo Li1,†
- 1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
- 2Department of Chemistry, University of North Carolina–Chapel Hill, Chapel Hill, NC 27599, USA.
- ↵†Corresponding author. Email: nicewicz{at}unc.edu (D.A.N.); ziboli{at}med.unc.edu (Z.L.)
↵* These authors contributed equally to this work.
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Science 21 Jun 2019:
Vol. 364, Issue 6446, pp. 1170-1174
DOI: 10.1126/science.aav7019
Vol. 364, Issue 6446, pp. 1170-1174
DOI: 10.1126/science.aav7019
Wei Chen
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
Zeng Huang
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
Nicholas E. S. Tay
2Department of Chemistry, University of North Carolina–Chapel Hill, Chapel Hill, NC 27599, USA.
Benjamin Giglio
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
Mengzhe Wang
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
Hui Wang
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
Zhanhong Wu
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
David A. Nicewicz
2Department of Chemistry, University of North Carolina–Chapel Hill, Chapel Hill, NC 27599, USA.
Zibo Li
1Biomedical Research Imaging Center, Department of Radiology, and UNC Lineberger Comprehensive Cancer Center, University of North Carolina–Chapel Hill, Chapel Hill, NC 27514, USA.
