Research Article

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

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Science  28 Jun 2019:
Vol. 364, Issue 6447, eaaw2872
DOI: 10.1126/science.aaw2872

Article Information

vol. 364 no. 6447

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History: 
  • Received for publication December 5, 2018
  • Accepted for publication May 23, 2019
  • .

Author Information

  1. Rémi Buisson1,2,
  2. Adam Langenbucher1,
  3. Danae Bowen2,
  4. Eugene E. Kwan1,
  5. Cyril H. Benes1,
  6. Lee Zou1,3,*,
  7. Michael S. Lawrence1,3,4,*
  1. 1Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  2. 2Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, CA, USA.
  3. 3Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  4. 4Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  1. *Corresponding author. Email: lzou1{at}mgh.harvard.edu (L.Z.); mslawrence{at}mgh.harvard.edu (M.S.L.)

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