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A proof of concept for structure-based vaccine design targeting RSV in humans

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Science  02 Aug 2019:
Vol. 365, Issue 6452, pp. 505-509
DOI: 10.1126/science.aav9033

Article Information

vol. 365 no. 6452 505-509

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History: 
  • Received for publication October 31, 2018
  • Resubmitted March 15, 2019
  • Accepted for publication July 8, 2019
  • .

Author Information

  1. Michelle C. Crank1,*,
  2. Tracy J. Ruckwardt1,*,
  3. Man Chen1,*,
  4. Kaitlyn M. Morabito1,
  5. Emily Phung1,2,
  6. Pamela J. Costner1,
  7. LaSonji A. Holman1,
  8. Somia P. Hickman1,
  9. Nina M. Berkowitz1,
  10. Ingelise J. Gordon1,
  11. Galina V. Yamshchikov1,
  12. Martin R. Gaudinski1,
  13. Azad Kumar1,
  14. Lauren A. Chang1,
  15. Syed M. Moin1,
  16. Juliane P. Hill1,,
  17. Anthony T. DiPiazza1,
  18. Richard M. Schwartz1,,
  19. Lisa Kueltzo1,
  20. Jonathan W. Cooper1,
  21. Peifeng Chen1,
  22. Judith A. Stein1,
  23. Kevin Carlton1,
  24. Jason G. Gall1,
  25. Martha C. Nason3,
  26. Peter D. Kwong1,
  27. Grace L. Chen1,
  28. John R. Mascola1,
  29. Jason S. McLellan4,
  30. Julie E. Ledgerwood1,
  31. Barney S. Graham1,§,
  32. the VRC 317 Study Team
  1. §Corresponding author. Email: bgraham{at}nih.gov
    1. 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
    2. 2Institute for Biomedical Sciences, George Washington University, Washington, DC 20052, USA.
    3. 3Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA.
    4. 4Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USA.
    1. * These authors contributed equally to this work.

    • Present address: Cytek Biosciences, Fremont, CA 94538, USA.

    • Present address: CRISPR Therapeutics AG, Cambridge, MA 02139, USA.

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