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Time-resolved crystallography reveals allosteric communication aligned with molecular breathing

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Science  13 Sep 2019:
Vol. 365, Issue 6458, pp. 1167-1170
DOI: 10.1126/science.aaw9904

Article Information

vol. 365 no. 6458 1167-1170

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History: 
  • Received for publication February 12, 2019
  • Accepted for publication August 21, 2019
  • .

Author Information

  1. Pedram Mehrabi1,2,3,*,
  2. Eike C. Schulz1,*,
  3. Raison Dsouza1,4,
  4. Henrike M. Müller-Werkmeister1,5,
  5. Friedjof Tellkamp6,
  6. R. J. Dwayne Miller1,7,,
  7. Emil F. Pai2,3,8,
  1. 1Department for Atomically Resolved Dynamics, Max-Planck-Institute for Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.
  2. 2Department of Medical Biophysics, University of Toronto, 101 College Street, Toronto, Ontario M5G 1L7, Canada.
  3. 3The Campbell Family Cancer Research Institute, Ontario Cancer Institute, 101 College Street, Toronto, Ontario M5G 1L7, Canada.
  4. 4Department of Physics, University of Hamburg, Jungiusstrasse 9, 20355 Hamburg, Germany.
  5. 5Institute of Chemistry - Physical Chemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
  6. 6Scientific Support Unit Machine Physics, Max-Planck-Institute for Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.
  7. 7Departments of Chemistry and Physics, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
  8. 8Departments of Biochemistry and Molecular Genetics, University of Toronto, 1 King’s College Circle, Toronto, Ontario M5S 1A8, Canada.
  1. Corresponding author. Email: dwayne.miller{at}mpsd.mpg.de (R.J.D.M.); emil.pai{at}utoronto.ca (E.F.P.)
  1. * These authors contributed equally to this work.

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