Research Article

Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate

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Science  11 Oct 2019:
Vol. 366, Issue 6462, eaav5728
DOI: 10.1126/science.aav5728

Article Information

vol. 366 no. 6462

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History: 
  • Received for publication September 28, 2018
  • Resubmitted May 22, 2019
  • Accepted for publication September 4, 2019
  • .

Author Information

  1. Vinidhra Mani1,2,
  2. Shannon K. Bromley1,3,
  3. Tarmo Äijö4,
  4. Rut Mora-Buch1,3,
  5. Esteban Carrizosa1,3,5,
  6. Ross D. Warner1,
  7. Moustafa Hamze1,3,
  8. Debattama R. Sen2,6,
  9. Alexandra Y. Chasse1,
  10. Alina Lorant7,
  11. Jason W. Griffith1,3,
  12. Rod A. Rahimi1,3,
  13. Craig P. McEntee8,
  14. Kate L. Jeffrey3,9,
  15. Francesco Marangoni1,3,*,
  16. Mark A. Travis8,
  17. Adam Lacy-Hulbert7,
  18. Andrew D. Luster1,3,
  19. Thorsten R. Mempel1,3,
  1. 1Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.
  2. 2Immunology Graduate Program, Harvard Medical School, Boston, MA, USA.
  3. 3Harvard Medical School, Boston, MA, USA.
  4. 4Center for Computational Biology, Flatiron Institute, New York, NY, USA.
  5. 5Bluebird Bio, 60 Binney Street, Cambridge, MA 02142, USA.
  6. 6Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  7. 7Benaroya Research Institute, Seattle, WA, USA.
  8. 8Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
  9. 9Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA, USA.
  1. Corresponding author. Email: tmempel{at}mgh.harvard.edu
  • * Present Address: University of California Irvine, Irvine, CA 92697, USA.

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