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Crossing the line

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Science  01 Nov 2019:
Vol. 366, Issue 6465, pp. 562-565
DOI: 10.1126/science.366.6465.562

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Summary

Russian geneticist Denis Rebrikov has stirred international controversy by pursuing an experiment that many believe is premature and dangerous: using the genome editor CRISPR to modify a gene in human embryos with the intention of bringing them to term. Science went to Russia to meet with Rebrikov, geneticists, government officials, and bioethicists, many of whom are sharply critical of the idea. Rebrikov spelled out his detailed, step-by-step scientific plan to correct a mutation that causes deafness. He insisted he would not attempt to move forward without supporting data, as well as ethical and regulatory review and approval.

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