Research Article

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex

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Science  22 Nov 2019:
Vol. 366, Issue 6468, pp. 971-977
DOI: 10.1126/science.aax0364

Article Information

vol. 366 no. 6468 971-977

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History: 
  • Received for publication February 15, 2019
  • Accepted for publication October 23, 2019
  • .

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Author Information

  1. Rosalie E. Lawrence1,2,*,
  2. Simon A. Fromm1,*,
  3. Yangxue Fu1,
  4. Adam L. Yokom1,
  5. Do Jin Kim1,
  6. Ashley M. Thelen1,2,
  7. Lindsey N. Young1,
  8. Chun-Yan Lim1,2,
  9. Avi J. Samelson2,3,
  10. James H. Hurley1,4,5,,
  11. Roberto Zoncu1,2,4,
  1. 1Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  2. 2The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA 94720, USA.
  3. 3Institute for Neurodegenerative Diseases, University of California at San Francisco, San Francisco, CA 94158, USA.
  4. 4California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA.
  5. 5Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  1. Corresponding author. Email: jimhurley{at}berkeley.edu (J.H.H.); rzoncu{at}berkeley.edu (R.Z.)
  1. * These authors contributed equally to this work.

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