Research Article

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

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Science  06 Dec 2019:
Vol. 366, Issue 6470, eaax4380
DOI: 10.1126/science.aax4380

Article Information

vol. 366 no. 6470

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History: 
  • Received for publication March 22, 2019
  • Accepted for publication October 17, 2019
  • .

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Author Information

  1. Jon M. Steichen1,2,3,*,
  2. Ying-Cing Lin4,*,
  3. Colin Havenar-Daughton3,5,*,
  4. Simone Pecetta4,*,
  5. Gabriel Ozorowski2,3,6,*,
  6. Jordan R. Willis1,2,3,*,
  7. Laura Toy3,5,
  8. Devin Sok1,2,3,
  9. Alessia Liguori1,2,3,
  10. Sven Kratochvil4,
  11. Jonathan L. Torres2,3,6,
  12. Oleksandr Kalyuzhniy1,2,3,
  13. Eleonora Melzi4,
  14. Daniel W. Kulp1,2,3,7,
  15. Sebastian Raemisch1,2,3,
  16. Xiaozhen Hu1,2,3,
  17. Steffen M. Bernard2,3,6,
  18. Erik Georgeson1,2,3,
  19. Nicole Phelps1,2,3,
  20. Yumiko Adachi1,2,3,
  21. Michael Kubitz1,2,3,
  22. Elise Landais1,2,3,
  23. Jeffrey Umotoy1,2,3,
  24. Amanda Robinson1,2,3,
  25. Bryan Briney1,2,3,8,
  26. Ian A. Wilson2,3,6,9,
  27. Dennis R. Burton1,2,3,
  28. Andrew B. Ward2,3,6,
  29. Shane Crotty3,5,10,,
  30. Facundo D. Batista4,11,,
  31. William R. Schief1,2,3,4,
  1. 1Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  5. 5Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  6. 6Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  7. 7Vaccine and Immune Therapy Center, The Wistar Institute, Philadelphia, PA 19104, USA.
  8. 8Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  9. 9Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  10. 10Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
  11. 11Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  1. Corresponding author. Email: schief{at}scripps.edu (W.R.S.); fbatista1{at}mgh.harvard.edu (F.D.B.); shane{at}lji.org (S.C.)
  1. * These authors contributed equally to this work.

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Oct 20191067321117
Nov 2019791019021263
Dec 2019773222601333
Jan 20202256608357
Feb 20202049411396
Mar 202094318695
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