Research Article

VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance

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Science  17 Jan 2020:
Vol. 367, Issue 6475, eaay0524
DOI: 10.1126/science.aay0524

Article Information

vol. 367 no. 6475

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History: 
  • Received for publication May 15, 2019
  • Resubmitted July 30, 2019
  • Accepted for publication December 2, 2019
  • .

Author Information

  1. Mohamed A. ElTanbouly1,*,
  2. Yanding Zhao2,3,*,
  3. Elizabeth Nowak1,
  4. Jiannan Li4,
  5. Evelien Schaafsma2,3,
  6. Isabelle Le Mercier5,
  7. Sabrina Ceeraz6,
  8. J. Louise Lines1,
  9. Changwei Peng7,8,
  10. Catherine Carriere9,
  11. Xin Huang9,
  12. Maria Day9,
  13. Brent Koehn10,
  14. Sam W. Lee11,
  15. Milagros Silva Morales7,
  16. Kristin A. Hogquist7,8,
  17. Stephen C. Jameson7,8,
  18. Daniel Mueller7,8,
  19. Jay Rothstein9,
  20. Bruce R. Blazar10,12,
  21. Chao Cheng3,13,,
  22. Randolph J. Noelle1,9,
  1. 1Department of Microbiology and Immunology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
  2. 2Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
  3. 3Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
  4. 4Adimab LLC, Lebanon, NH, USA.
  5. 5KSQ Therapeutics, Cambridge, MA, USA.
  6. 6Immunology Discovery, Janssen Research and Development LLC, Spring House, PA, USA.
  7. 7Division of Rheumatic and Autoimmune Diseases, Center for Immunology, University of Minnesota, Minneapolis, MN, USA.
  8. 8The Center for Immunology, University of Minnesota, Minneapolis, MN, USA.
  9. 9ImmuNext Corporation, Lebanon, NH, USA.
  10. 10Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
  11. 11Yale University School of Medicine, New Haven, CT, USA.
  12. 12Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  13. 13Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  1. Corresponding author. Email: rjn{at}dartmouth.edu (R.J.N.); chao.cheng{at}bcm.edu (C.C.)
  1. * These authors contributed equally to this work.

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